A bőr alkotórésze. Megállapították, hogy összefüggés van a víztartalom és a hyaluronsav – tartalom között. Idősebb korban megfigyelhető a bőr hyaluronsav- tartalmának csökkenése. A természetes kötőszövetben a hyaluronsav szorosan kapcsolódik a proteinekhez és a →mukopoliszacharidokhoz. Fontos kozmetikai hatóanyag. →Akne kezelés, Ránckezelés.
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